Wednesday, September 26, 2012

Therapeutic


Generic Name: coal tar topical (KOL TAR TOP ik al)

Brand Names: Balnetar, Betatar Gel, Coal Tar, Cutar, Denorex, Denorex Dry Scalp, Denorex Extra Strength, Denorex Medicated Shampoo and Conditioner, DHS Tar Shampoo, Doak Tar, Doak Tar Oil, Elta Tar, Fototar, G-TAR, Ionil T, Ionil T Plus, MG 217 Psoriasis, MG217 Medicated Tar, Neutrogena T/Derm, Neutrogena T/Gel, Neutrogena T/Gel Extra Strength, Oxipor VHC, PC Tar, Pentrax, Pentrax Gold, Polytar, Psoriasin, Psorigel, T/Gel Conditioner, Tegrin Medicated, Tegrin Medicated Soap, Therapeutic, Theraplex T, Zetar


What is coal tar?

Coal tar is a by-product of coal processing.


Coal tar topical (for the skin) is used to treat the skin symptoms of psoriasis, including dryness, redness, flaking, scaling, and itching. Coal tar is not a cure for psoriasis, and it will provide only temporary relief of skin symptoms.


Coal tar may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about coal tar?


You should not use this medication if you are allergic to coal tar.

Before using coal tar, tell your doctor if you are allergic to any drugs, or if you are receiving ultraviolet radiation treatment for your psoriasis.


Do not use coal tar to treat the skin of your groin or rectal area.


Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Coal tar can make your skin more sensitive to sunlight and sunburn may result. Stop using coal tar and call your doctor at once if you have severe stinging, burning, swelling, or other irritation of the treated skin. Do not use coal tar to treat large skin areas. Do not use coal tar over long periods of time without your doctor's advice.

Call your doctor if your symptoms do not improve, or if they get worse after using coal tar.


Coal tar is not a cure for psoriasis, and it will provide only temporary relief of skin symptoms.


What should I discuss with my health care provider before using coal tar?


You should not use this medication if you are allergic to coal tar.

Before using coal tar, tell your doctor if you are allergic to any drugs, or if you are receiving ultraviolet radiation treatment for your psoriasis.


This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether coal tar passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Coal tar products may contain lanolin, mineral oil, or other emulsifiers. Check the label of any coal tar product you are using. Talk with your doctor before using coal tar if you are allergic to any of the ingredients.


How should I use coal tar?


Use this medication as directed on the label, or as your doctor has prescribed. Do not use the medication in larger amounts or for longer than recommended.


Apply coal tar cream, lotion, ointment, or solution according the directions on the medication label. Some forms of coal tar may be applied 1 to 4 times per day.


To use coal tar bath oil, pour 1 to 3 capfuls into a warm bath before bathing. The oil can make the bathtub slippery. Take care to avoid a fall.


Shake the coal tar shampoo well just before each use. Use enough shampoo to create a rich lather. Massage the shampoo into your scalp and rinse thoroughly. Apply the shampoo a second time and leave it on your scalp for 5 minutes. Rinse thoroughly. Do not use coal tar to treat large skin areas. Do not use coal tar over long periods of time without your doctor's advice.

Call your doctor if your symptoms do not improve, or if they get worse after using coal tar.


Coal tar shampoo may discolor blond or colored hair. This effect is usually temporarily.


Some forms of coal tar can stain fabric or other surfaces.


Store coal tar at room temperature away from moisture and heat. Keep the medicine tightly closed with not in use.

What happens if I miss a dose?


Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a coal tar overdose are not known.


What should I avoid while using coal tar?


Avoid getting this medication in your eyes. If this does occur, rinse with water.

Do not use coal tar to treat the skin of your groin or rectal area.


Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Coal tar can make your skin more sensitive to sunlight and sunburn may result.

Coal tar side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using coal tar and call your doctor at once if you have severe stinging, burning, swelling, or other irritation of the treated skin.

Less serious side effects may include mild skin irritation or skin rash.


This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect coal tar?


Do not use coal tar together with other psoriasis medications unless your doctor tells you to.

There may be other drugs that can interact with coal tar. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.



More Therapeutic resources


  • Therapeutic Use in Pregnancy & Breastfeeding
  • Therapeutic Support Group
  • 0 Reviews for Therapeutic - Add your own review/rating


  • Betatar Gel Topical Advanced Consumer (Micromedex) - Includes Dosage Information

  • Coal Tar Foam MedFacts Consumer Leaflet (Wolters Kluwer)

  • Denorex Shampoo MedFacts Consumer Leaflet (Wolters Kluwer)

  • Doak Tar Shampoo MedFacts Consumer Leaflet (Wolters Kluwer)

  • Fototar Ointment MedFacts Consumer Leaflet (Wolters Kluwer)

  • MG217 Medicated Tar Lotion MedFacts Consumer Leaflet (Wolters Kluwer)

  • Psoriasin Prescribing Information (FDA)



Compare Therapeutic with other medications


  • Dermatitis
  • Psoriasis
  • Seborrheic Dermatitis


Where can I get more information?


  • Your pharmacist can provide more information about coal tar.



Terbinafine topical



Generic Name: terbinafine topical (ter BIN a feen TOP i kal)

Brand names: Athlete's Foot Cream, LamISIL AT, LamISIL AT Athletes Foot, LamISIL AT Jock Itch, LamISIL Topical, Desenex Maximum


What is terbinafine topical?

Terbinafine is an antifungal medication. Terbinafine topical prevents fungus from growing on the skin.


Terbinafine topical (for the skin) is used to treat skin infections such as athlete's foot, jock itch, and ringworm infections.


Terbinafine topical may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about terbinafine topical?


Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.


Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to.


Avoid getting this medication in your mouth or eyes.

What should I discuss with my healthcare provider before using terbinafine topical?


You should not use this medication if you are allergic to it. It is not known whether terbinafine topical will be harmful to an unborn baby. Do not use terbinafine topical without first talking to your doctor if you are pregnant. It is not known whether terbinafine topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use terbinafine topical?


Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.


Wash your hands before and after using this medication.

Clean and dry the affected area. Apply the medication as directed.


Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.


For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after a few weeks of treatment.


Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to.


Store terbinafine topical at room temperature away from moisture and heat.

What happens if I miss a dose?


Apply the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not apply extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of terbinafine topical is not likely to cause life-threatening symptoms.


What should I avoid while using terbinafine topical?


Avoid getting this medication in your mouth or eyes. If it does get into any of these areas, rinse with water.

Avoid using other medications on the areas you treat with terbinafine topical unless your doctor has told you to.


Avoid wearing tight-fitting, synthetic clothing that doesn't allow air circulation. Wear loose-fitting clothing made of cotton and other natural fibers until your infection is healed.


Terbinafine topical side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using terbinafine topical and call your doctor at once if you have a serious side effect such as severe blistering, itching, redness, peeling, dryness, or irritation of the skin.

Less serious side effects are more likely, and you may have none at all.


This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Terbinafine topical Dosing Information


Usual Adult Dose for Tinea Corporis:

Cream, gel, spray: Apply to the affected area once a day.

Usual Adult Dose for Tinea Cruris:

Cream, gel, spray: Apply to the affected area once a day.

Usual Adult Dose for Tinea Pedis:

Cream, spray: Apply to the affected area twice a day.
Gel: Apply to the affected area once a day.

Usual Adult Dose for Tinea Versicolor:

Solution: Apply to the affected area twice a day.

Usual Pediatric Dose for Tinea Corporis:

12 years or older:
Cream, gel, spray: Apply to the affected area once a day.

Usual Pediatric Dose for Tinea Cruris:

12 years or older:
Cream, gel, spray: Apply to the affected area once a day.

Usual Pediatric Dose for Tinea Pedis:

12 years or older:
Cream, spray: Apply to the affected area twice a day.
Gel: Apply to the affected area once a day.


What other drugs will affect terbinafine topical?


It is not likely that other drugs you take orally or inject will have an effect on topically applied terbinafine topical. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.



More terbinafine topical resources


  • Terbinafine topical Dosage
  • Terbinafine topical Use in Pregnancy & Breastfeeding
  • Terbinafine topical Support Group
  • 5 Reviews for Terbinafine - Add your own review/rating


  • Lamisil AT Prescribing Information (FDA)

  • Lamisil AT Topical Advanced Consumer (Micromedex) - Includes Dosage Information

  • Lamisil AT Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • Lamisil AT Jock Itch Prescribing Information (FDA)



Compare terbinafine topical with other medications


  • Tinea Corporis
  • Tinea Cruris
  • Tinea Pedis
  • Tinea Versicolor


Where can I get more information?


  • Your pharmacist has additional information about terbinafine topical written for health professionals that you may read.



Friday, September 21, 2012

Tenofovir


Generic Name: tenofovir (ten OF oh vir)

Brand Names: Viread


What is tenofovir?

Tenofovir is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.


Tenofovir is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Tenofovir is not a cure for HIV or AIDS. Tenofovir is also used to treat chronic hepatitis B.


Tenofovir may also be used for purposes not listed in this medication guide.


What is the most important information I should know about tenofovir?


Do not take other medicines that also contain tenofovir (such as Truvada). Some people develop lactic acidosis while taking tenofovir. Early symptoms may get worse over time and this condition can be fatal. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, fast or uneven heart rate, dizziness, or feeling very weak or tired. Tenofovir can also cause severe or fatal liver problems. Symptoms include nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). Call your doctor at once if you have any of these symptoms.

If you have hepatitis B you may develop liver symptoms after you stop taking this medication, even months after stopping. Your doctor may want to check your liver function for several months after you stop using tenofovir. Visit your doctor regularly.


HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.


What should I discuss with my healthcare provider before taking tenofovir?


Do not use this medication if you have ever had an allergic reaction to a medicine containing tenofovir, including Truvada.

You should not take tenofovir if you are also taking Truvada (emtricitabine/tenofovir) or adefovir (Hepsera).


To make sure you can safely take tenofovir, tell your doctor if you have any of these other conditions:


  • liver disease (including hepatitis B);

  • kidney disease; or


  • bone problems (such as osteopenia).




Some people develop a life-threatening condition called lactic acidosis while taking tenofovir. You may be more likely to develop lactic acidosis if you are overweight or have liver disease, if you are a woman, or if you have taken HIV or AIDS medications for a long time. Talk with your doctor about your individual risk. Tenofovir can also cause severe or fatal liver problems. Symptoms include nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). Call your doctor at once if you have any of these symptoms. FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby, but HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of tenofovir on the baby.


Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk. Tenofovir should not be given to a child unless your doctor has told you otherwise.

How should I take tenofovir?


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.


Take tenofovir with a full glass of water.

Tenofovir can be taken with or without food.


Use tenofovir regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.


To be sure this medicine is helping your condition and is not causing harmful effects, your blood will need to be tested often. Your liver and kidney function may also need to be tested. Visit your doctor regularly.


If you have hepatitis B you may develop liver symptoms after you stop taking this medication, even months after stopping. Your doctor may want to check your liver function for several months after you stop using tenofovir. Visit your doctor regularly.


Store at room temperature away from moisture, heat, and direct light.

See also: Tenofovir dosage (in more detail)

What happens if I miss a dose?


Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking tenofovir?


Avoid drinking alcohol. It may increase your risk of liver damage. Taking this medication will not prevent you from passing HIV to other people. Avoid having unprotected sex or sharing razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

Tenofovir side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, fast or uneven heart rate, dizziness, or feeling very weak or tired. Call your doctor at once if you have a serious side effect such as:

  • liver damage - nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);




  • kidney problems - increased thirst and urination, loss of appetite, weakness, constipation, urinating less than usual or not at all;




  • fever, chills, body aches, flu symptoms; or




  • any other signs of new infection.



Less serious side effects may include:



  • sleep problems (insomnia), strange dreams;




  • depression, headache, dizziness;




  • diarrhea, bloating, gas;




  • muscle or joint pain;




  • skin rash; or




  • changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and trunk).



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Tenofovir Dosing Information


Usual Adult Dose for HIV Infection:

300 mg orally once a day

Usual Adult Dose for Chronic Hepatitis B:

300 mg orally once a day
The optimum duration of treatment is not known.

Usual Adult Dose for Nonoccupational Exposure:

300 mg orally once a day plus efavirenz plus (emtricitabine or lamivudine)
Prophylaxis should be initiated as soon as possible, within 72 hours of exposure.
Duration: 28 days

Usual Pediatric Dose for HIV Infection:

12 years or older with body weight 35 kg or more: 300 mg orally once a day


What other drugs will affect tenofovir?


Tell your doctor about all other medicines you use, especially:



  • amphotericin B (Fungizone, AmBisome, Amphotec, Abelcet);




  • pentamidine (Nebupent, Pentam);




  • tacrolimus (Prograf);




  • antibiotics such as capreomycin (Capastat), rifampin (Rifadin, Rimactane, Rifater), vancomycin (Vancocin, Vancoled);




  • antiviral medicines such as acyclovir (Zovirax), cidofovir (Vistide), foscarnet (Foscavir), ganciclovir (Cytovene), valacyclovir (Valtrex), or valganciclovir (Valcyte);




  • aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Voltaren), indomethacin, naproxen (Aleve, Naprosyn), piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others;




  • cancer medicine such as aldesleukin (Proleukin), carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), streptozocin (Zanosar), or tretinoin (Vesanoid); or




  • other HIV or AIDS medications such as atazanavir (Reyataz), didanosine (Videx), lopinavir and ritonavir (Kaletra).



This list is not complete and other drugs may interact with tenofovir. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.



More tenofovir resources


  • Tenofovir Side Effects (in more detail)
  • Tenofovir Dosage
  • Tenofovir Use in Pregnancy & Breastfeeding
  • Tenofovir Drug Interactions
  • Tenofovir Support Group
  • 2 Reviews for Tenofovir - Add your own review/rating


  • tenofovir Advanced Consumer (Micromedex) - Includes Dosage Information

  • Tenofovir MedFacts Consumer Leaflet (Wolters Kluwer)

  • Tenofovir Disoproxil Fumarate Monograph (AHFS DI)

  • Viread Prescribing Information (FDA)

  • Viread Consumer Overview



Compare tenofovir with other medications


  • Hepatitis B
  • HIV Infection
  • Nonoccupational Exposure


Where can I get more information?


  • Your pharmacist can provide more information about tenofovir.

See also: tenofovir side effects (in more detail)



Thursday, September 20, 2012

Soothe & Cool Skin Paste


Generic Name: zinc oxide topical (ZINK OX ide)

Brand Names: ARC, Balmex, Boudreaux Butt Paste, Caldesene, Calmol-4 Suppository, Critic-Aid Skin Paste, Delazinc, Dermagran BC, Desitin, Desitin Maximum Strength Original, Desitin Rapid Relief Creamy, Diaper Rash Ointment, Diaper Relief, Dr. Smith's Diaper, Flanders Buttocks Ointment, Geri-Protect, Medi-Paste, PeriGuard, Pinxav, Rash Relief, RVPaque, Seniortopix Healix, Soothe & Cool Skin Paste, Sportz Block Dark, Sportz Block Light, Sportz Block Medium, Triple Paste, Tronolane Suppositories, Unna-Flex Elastic Unna Boot 3 inch, Unna-Flex Elastic Unna Boot 4 inch, Znlin


What is Soothe & Cool Skin Paste (zinc oxide topical)?

Zinc oxide is a mineral.


Zinc oxide topical (for the skin) is used to treat diaper rash, minor burns, severely chapped skin, or other minor skin irritations.


Zinc oxide rectal suppositories are used to treat itching, burning, irritation, and other rectal discomfort caused by hemorrhoids or painful bowel movements.


Zinc oxide topical may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Soothe & Cool Skin Paste (zinc oxide topical)?


You should not use this medication if you are allergic to zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax.

Zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing skin lesions.


Keep the diaper area clean and dry to prevent worsening of skin rash. Change wet diapers as soon as possible. Allow the skin to dry thoroughly before putting on a fresh diaper.


Stop using this medication and call your doctor if your condition does not improve within 7 days of treatment. Avoid getting this medication in your mouth or eyes. If this does happen, rinse with water right away. Do not use zinc oxide topical on deep skin wounds or severe burns. Get medical attention for more severe skin irritation or injury.

Avoid using other medications on the areas you treat with zinc oxide unless you doctor tells you to.


What should I discuss with my health care provider before using Soothe & Cool Skin Paste (zinc oxide topical)?


You should not use this medication if you are allergic to zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax.

Zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing skin lesions.


It is not known whether zinc oxide topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether zinc oxide topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without medical advice if you are breast-feeding a baby.

How should I use Soothe & Cool Skin Paste (zinc oxide topical)?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.


Apply enough of this medication to cover the entire area to be treated. Zinc oxide often leaves a thin white residue that may not be entirely rubbed in.


To treat chapped skin, minor burn wounds, or other skin irritations, use the medication as often as needed. Apply a thin layer to the affected area and rub in gently.


To treat diaper rash, use this medication each time the diaper is changed. It is especially important to apply the medication at bedtime or whenever there will be a long period of time between diaper changes.


Keep the diaper area clean and dry to prevent worsening of skin rash. Change wet diapers as soon as possible. Allow the skin to dry thoroughly before putting on a fresh diaper.


When using the powder form of this medicine, pour the powder slowly to avoid a large puff into the air. Do not allow a baby to handle a powder bottle during use. Always close the lid after using the powder.

Zinc oxide rectal suppositories come with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.


Wash your hands before and after inserting a rectal suppository.

Try to empty your bowel and bladder just before using the suppository. Cleanse and dry your rectal area thoroughly.


Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.


For best results, stay lying down after inserting the suppository and hold it in your rectum for a few minutes. The suppository will melt quickly once inserted and you should feel little or no discomfort while holding it in.


Stop using this medication and call your doctor if your condition does not improve within 7 days of treatment. Store at room temperature away from moisture and heat. Keep the tube cap tightly closed when not in use. You may store zinc oxide rectal suppositories in a refrigerator to prevent melting.

What happens if I miss a dose?


Since zinc oxide is used on an as needed basis, you are not likely to miss a dose. Using extra zinc oxide to make up a missed dose will not make the medication more effective.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Soothe & Cool Skin Paste (zinc oxide topical)?


Avoid getting this medication in your mouth or eyes. If this does happen, rinse with water right away. Do not use zinc oxide topical on deep skin wounds or severe burns. Get medical attention for more severe skin irritation or injury.

Soothe & Cool Skin Paste (zinc oxide topical) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using zinc oxide rectal suppositories if you have rectal bleeding or continued pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Soothe & Cool Skin Paste (zinc oxide topical)?


Avoid applying other skin medications on the same treatment area with zinc oxide, unless your doctor has told you to.


There may be other drugs that can interact with zinc oxide topical or rectal suppositories. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Soothe & Cool Skin Paste resources


  • Soothe & Cool Skin Paste Side Effects (in more detail)
  • Soothe & Cool Skin Paste Use in Pregnancy & Breastfeeding
  • 0 Reviews for Soothe & Cool Skin - Add your own review/rating


  • Arcalyst Monograph (AHFS DI)

  • Caldesene Topical Advanced Consumer (Micromedex) - Includes Dosage Information

  • Desitin Cream MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Soothe & Cool Skin Paste with other medications


  • Anal Itching
  • Dermatologic Lesion
  • Diaper Rash


Where can I get more information?


  • Your pharmacist can provide more information about zinc oxide topical.

See also: Soothe & Cool Skin side effects (in more detail)



Tuesday, September 18, 2012

Synthetic Conjugated Estrogens, A vaginal


Generic Name: conjugated estrogens (vaginal) (KON joo gay ted ES troe jenz)

Brand Names: Premarin Vaginal, Synthetic Conjugated Estrogens, A


What are vaginal conjugated estrogens?

Estrogen is a female sex hormone produced by the ovaries. Estrogen is necessary for many processes in the body.


Vaginal conjugated estrogens are a mixture of estrogen hormones used to treat the vaginal symptoms of menopause such as dryness, burning, irritation, and painful sexual intercourse.


Vaginal conjugated estrogens should not be used to prevent heart disease or dementia, because this medication may actually increase your risk of developing these conditions.

Vaginal conjugated estrogens may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about vaginal conjugated estrogens?


This medication can cause birth defects in an unborn baby. Do not use vaginal conjugated estrogens if you are pregnant. Do not use this medication if you have any of the following conditions: a history of heart attack, stroke, or blood clot (especially in your lung or your lower body), liver disease, abnormal vaginal bleeding, or a hormone-related cancer such as breast or uterine cancer.

Long-term treatment with conjugated estrogens may increase your risk of breast cancer, heart attack, or stroke. Talk with your doctor about your individual risks before using vaginal conjugated estrogens long term, especially if you smoke or are overweight. Your doctor should check your progress on a regular basis (every 3 to 6 months) to determine whether you should continue this treatment.


Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using vaginal conjugated estrogens.


Vaginal conjugated estrogens should not be used to prevent heart disease or dementia, because this medication may actually increase your risk of developing these conditions.

What should I discuss with my healthcare provider before using vaginal conjugated estrogens?


Do not use vaginal conjugated estrogens if you are pregnant, or if you have:

  • a history of heart attack, stroke, or blood clot (especially in your lung or your lower body);




  • abnormal vaginal bleeding that a doctor has not checked;




  • liver disease; or




  • any type of breast, uterine, or hormone-dependent cancer.



Before using vaginal conjugated estrogens, tell your doctor if you are allergic to any drugs, or if you have:



  • high blood pressure, heart disease, or circulation problems;




  • a personal or family history of stroke;




  • endometriosis;



  • liver or kidney disease;


  • asthma;




  • epilepsy or other seizure disorder;




  • migraines;




  • diabetes;




  • underactive thyroid;




  • high cholesterol or triglycerides;




  • high or low levels of calcium in your blood;




  • porphyria;




  • systemic lupus erythematosus (SLE);




  • gallbladder disease; or




  • if you have had your uterus removed (hysterectomy).



Vaginal conjugated estrogens increase your risk of developing endometrial hyperplasia, a condition that may lead to cancer of the uterus. Taking progestins while using conjugated estrogens may lower this risk. If your uterus has not been removed, your doctor may prescribe a progestin for you to take while you are using vaginal conjugated estrogens.


Long-term conjugated estrogens treatment may increase your risk of stroke or blood clots. Talk with your doctor about your individual risks before using vaginal conjugated estrogens long term, especially if you smoke or are overweight. Your doctor should check your progress on a regular basis (every 3 to 6 months) to determine whether you should continue this treatment.


FDA pregnancy category X. This medication can cause birth defects. Do not use vaginal conjugated estrogens if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. You should know that conjugated estrogens vaginal cream can weaken the latex of a condom, diaphragm, or cervical cap. Talk to your doctor about the best contraceptive methods to use. Conjugated estrogens can pass into breast milk and may harm a nursing baby. This medication may also slow breast milk production. Do not use if you are breast-feeding a baby. Do not use this medication in anyone under 18 years old without the advice of a doctor.

How should I use vaginal conjugated estrogens?


Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label.


Vaginal conjugated estrogens are usually prescribed for only a short time and are most often used in a cycle, such as 3 weeks on followed by 1 week off. Some conditions require daily use and others require use only twice a week during the treatment period. Follow the directions on your prescription label.


To apply this medication, use only the vaginal applicator provided. After each use, take the applicator apart and clean it with mild soap and warm water. Do not use hot or boiling water.


Have regular physical exams and self-examine your breasts for lumps on a monthly basis if you are using vaginal conjugated estrogens long term.


If you need to have any type of surgery, tell the surgeon ahead of time that you are using conjugated estrogens. You may need to stop using the medicine for a short time.


This medication can affect the results of certain medical tests. Tell any doctor who treats you that you are using conjugated estrogens.


Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?


Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use your medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include nausea, vomiting, or vaginal bleeding.

What should I avoid while using vaginal conjugated estrogens?


Do not smoke while using this medication. Smoking can increase your risk of blood clots, stroke, or heart attack caused by vaginal conjugated estrogens.


Vaginal conjugated estrogens side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;




  • sudden numbness or weakness, especially on one side of the body;




  • sudden headache, confusion, problems with vision, speech, or balance;




  • pain or swelling in your lower leg;




  • abnormal vaginal bleeding;




  • migraine headache;




  • pain, swelling, or tenderness in your stomach;




  • confusion, problems with memory or concentration;




  • jaundice (yellowing of the skin or eyes);




  • swelling in your hands, ankles, or feet; or




  • a breast lump.



Less serious side effects may include:



  • mild nausea, vomiting, bloating, stomach cramps;




  • breast pain, tenderness, or swelling;




  • freckles or darkening of facial skin;




  • increased hair growth, loss of scalp hair;




  • changes in weight or appetite;




  • problems with contact lenses;




  • vaginal itching or discharge;




  • changes in your menstrual periods, decreased sex drive; or




  • headache, nervousness, dizziness, tired feeling.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect vaginal conjugated estrogens?


Before using conjugated estrogens, tell your doctor if you are using any of the following medicines:



  • a blood thinner such as warfarin (Coumadin);




  • a thyroid medication such as levothyroxine (Synthroid);




  • insulin or diabetes medicine taken by mouth;




  • rifampin (Rifadin, Rifater, Rifamate, Rimactane);




  • ketoconazole (Nizoral) or itraconazole (Sporanox);




  • seizure medicines such as phenytoin (Dilantin), carbamazepine (Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), or primidone (Mysoline);




  • a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Luminal, Solfoton); or




  • antidepressants such as amitriptyline (Elavil, Etrafon), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil).



This list is not complete and there may be other drugs that can interact with vaginal conjugated estrogens. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.



More Synthetic Conjugated Estrogens, A resources


  • Synthetic Conjugated Estrogens, A Side Effects (in more detail)
  • Synthetic Conjugated Estrogens, A Use in Pregnancy & Breastfeeding
  • Synthetic Conjugated Estrogens, A Drug Interactions
  • 0 Reviews for Synthetic Conjugated Estrogens, A - Add your own review/rating


Compare Synthetic Conjugated Estrogens, A with other medications


  • Atrophic Urethritis
  • Atrophic Vaginitis
  • Postmenopausal Symptoms


Where can I get more information?


  • Your pharmacist can provide more information about vaginal conjugated estrogens.

See also: Synthetic Conjugated Estrogens, A side effects (in more detail)



Friday, September 14, 2012

Surmontil


Generic Name: trimipramine (Oral route)

trye-MIP-ra-meen

Oral route(Capsule)

Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults in short-term studies with major depressive disorder (MDD) and other psychiatric disorders. Short term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24, and there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. This risk must be balanced with the clinical need. Monitor patients closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Not approved for use in pediatric patients .



Commonly used brand name(s)

In the U.S.


  • Surmontil

Available Dosage Forms:


  • Tablet

  • Capsule

Therapeutic Class: Antidepressant


Pharmacologic Class: Antidepressant, Tricyclic


Uses For Surmontil


Trimipramine is used to treat the symptoms of depression. It works on the central nervous system (CNS) to increase levels of certain chemicals in the brain. This medicine is a tricyclic antidepressant (TCA).


This medicine is available only with your doctor's prescription.


Before Using Surmontil


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of trimipramine in the pediatric population. Safety and efficacy have not been established.


Geriatric


Although appropriate studies on the relationship of age to the effects of trimipramine have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have unwanted effects (e.g., confusion or unusual drowsiness) or age-related heart, liver, or kidney problems, which may require caution in patients receiving trimipramine.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


  • Bepridil

  • Cisapride

  • Clorgyline

  • Dronedarone

  • Grepafloxacin

  • Isocarboxazid

  • Levomethadyl

  • Linezolid

  • Mesoridazine

  • Methylene Blue

  • Moclobemide

  • Phenelzine

  • Pimozide

  • Ranolazine

  • Selegiline

  • Sparfloxacin

  • Terfenadine

  • Thioridazine

  • Tranylcypromine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acecainide

  • Alfuzosin

  • Amiodarone

  • Amisulpride

  • Amitriptyline

  • Amoxapine

  • Amprenavir

  • Aprindine

  • Arsenic Trioxide

  • Asenapine

  • Astemizole

  • Atazanavir

  • Azimilide

  • Azithromycin

  • Bretylium

  • Chloral Hydrate

  • Chloroquine

  • Chlorpromazine

  • Ciprofloxacin

  • Citalopram

  • Clarithromycin

  • Clomipramine

  • Clonidine

  • Clozapine

  • Crizotinib

  • Dasatinib

  • Desipramine

  • Dextromethorphan

  • Disopyramide

  • Dofetilide

  • Dolasetron

  • Droperidol

  • Enflurane

  • Epinephrine

  • Erythromycin

  • Etilefrine

  • Flecainide

  • Fluconazole

  • Fluoxetine

  • Foscarnet

  • Gatifloxacin

  • Gemifloxacin

  • Granisetron

  • Halofantrine

  • Haloperidol

  • Halothane

  • Ibutilide

  • Iloperidone

  • Indacaterol

  • Iproniazid

  • Isoflurane

  • Isradipine

  • Lapatinib

  • Levofloxacin

  • Lidoflazine

  • Lopinavir

  • Lorcainide

  • Lumefantrine

  • Mefloquine

  • Methadone

  • Methoxamine

  • Midodrine

  • Moricizine

  • Moxifloxacin

  • Nefopam

  • Nialamide

  • Nilotinib

  • Norepinephrine

  • Norfloxacin

  • Nortriptyline

  • Octreotide

  • Ofloxacin

  • Ondansetron

  • Oxilofrine

  • Paliperidone

  • Pargyline

  • Pazopanib

  • Pentamidine

  • Perflutren Lipid Microsphere

  • Phenylephrine

  • Posaconazole

  • Procainamide

  • Procarbazine

  • Prochlorperazine

  • Promethazine

  • Propafenone

  • Protriptyline

  • Quetiapine

  • Quinidine

  • Quinine

  • Rasagiline

  • Risperidone

  • Saquinavir

  • Sematilide

  • Sertindole

  • Sertraline

  • Sodium Phosphate

  • Sodium Phosphate, Dibasic

  • Sodium Phosphate, Monobasic

  • Solifenacin

  • Sorafenib

  • Sotalol

  • Spiramycin

  • Sulfamethoxazole

  • Sultopride

  • Sunitinib

  • Tapentadol

  • Tedisamil

  • Telavancin

  • Telithromycin

  • Tetrabenazine

  • Toloxatone

  • Toremifene

  • Tramadol

  • Trazodone

  • Trifluoperazine

  • Trimethoprim

  • Vandetanib

  • Vardenafil

  • Vasopressin

  • Vemurafenib

  • Venlafaxine

  • Voriconazole

  • Ziprasidone

  • Zolmitriptan

  • Zotepine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acenocoumarol

  • Arbutamine

  • Atomoxetine

  • Cannabis

  • Dicumarol

  • Paroxetine

  • Phenprocoumon

  • S-Adenosylmethionine

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Bipolar disorder (mood disorder with alternating episodes of mania and depression), or risk of or

  • Heart attack, recent—Should not be used in patients with these conditions.

  • Diabetes or

  • Glaucoma, history of or

  • Heart disease or

  • Overactive thyroid or

  • Schizophrenia or

  • Seizures, history of or

  • Urinary retention (trouble urinating), history of—Use with caution. May make these conditions worse.

  • Liver disease—Use with caution. May increase chance for serious side effects.

Proper Use of Surmontil


Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.


Trimipramine can make you sleepy. Your doctor may tell you to take this medicine at bedtime.


This medicine comes with a medication guide. Read and follow the instructions in the guide carefully. Ask your doctor if you have any questions.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage form (capsules):
    • For depression:
      • Adults—At first, 75 milligrams (mg) in divided doses per day. Your doctor may increase your dose as needed. However, the dose is usually not more than 200 mg per day, unless you are in the hospital. Some hospitalized patients may need higher doses.

      • Teenagers and Older Adults—At first, 50 milligrams (mg) per day. Your doctor may increase your dose up to 100 mg per day.

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using Surmontil


It is very important that your doctor check your progress at regular visits to allow for changes in your dose and to check for any unwanted effects.


Trimipramine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away.


Do not take trimipramine if you have taken a monoamine oxidase (MAO) inhibitor (isocarboxazid [Marplan®], phenelzine [Nardil®], selegiline [Eldepryl®, or tranylcypromine [Parnate®]) in the past two weeks. Do not start taking a MAO inhibitor within two weeks of stopping trimipramine. If you do, you may develop confusion, agitation, restlessness, stomach or intestinal symptoms, sudden high body temperature, extremely high blood pressure, or severe convulsions.


Do not stop taking this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent a possible worsening of your condition and reduce the possibility of withdrawal symptoms such as headache, nausea, or a general feeling of discomfort or illness.


This medicine may cause some people to become drowsy. Make sure you know how you react to this medicine before you drive, use medicines, or do anything else that could be dangerous if you are drowsy or not alert.


Before having any kind of surgery, tell the medical doctor in charge that you are using this medicine. Taking trimipramine together with medicines used during surgery may increase the risk of side effects.


This medicine may affect blood sugar levels. If you notice a change in the results of your blood or urine sugar tests, or if you have any questions, check with your doctor.


This medicine will add to the effects of alcohol and other central nervous system (CNS) depressants (medicines that cause drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. This effect may last for a few days after you stop taking this medicine. Check with your doctor before taking any of the above while you are using this medicine.


Surmontil Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


Incidence not known
  • Abdominal or stomach pain

  • actions that are out of control

  • agitation

  • anxiety

  • black, tarry stools

  • bleeding and bruising

  • bleeding gums

  • blood in urine or stools

  • blurred vision

  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

  • chest pain or discomfort

  • clay-colored stools

  • cold sweats

  • coma

  • confusion about identity, place, and time

  • continuing ringing, buzzing, or other unexplained noise in ears

  • convulsions

  • cool, pale skin

  • cough or hoarseness

  • dark urine

  • decrease in frequency of urination

  • decreased urine output or volume

  • depression

  • difficulty in passing urine (dribbling)

  • difficulty in speaking

  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly

  • double vision

  • drooling

  • dry mouth

  • false beliefs that cannot be changed by facts

  • fast, pounding, or irregular heartbeat or pulse

  • fear or nervousness

  • feeling of warmth

  • feeling, seeing, or hearing things that are not there

  • feeling that others are watching you or controlling your behavior

  • feeling that others can hear your thoughts

  • fever with or without chills

  • flushed, dry skin

  • fruit-like breath odor

  • general feeling of tiredness or weakness

  • headache

  • hearing loss

  • hostility

  • hyperventilation

  • inability to move arms, legs, or facial muscles

  • inability to speak

  • increased hunger

  • increased need to urinate

  • increased thirst

  • increased urination

  • irritability

  • itching

  • lack of coordination

  • lethargy

  • loss of appetite

  • loss of balance control

  • lower back or side pain

  • mood or mental changes

  • muscle spasm or jerking of all extremities

  • muscle trembling or stiffness

  • muscle twitching

  • nausea

  • nightmares

  • pain or discomfort in arms, jaw, back, or neck

  • painful or difficult urination

  • passing urine more often

  • perspiration

  • pinpoint red or purple spots on skin

  • pounding in the ears

  • rapid weight gain

  • rash

  • redness of the face, neck, arms, and occasionally, upper chest

  • restlessness

  • seizures

  • shakiness and unsteady walk

  • shortness of breath

  • shuffling walk

  • sleeplessness

  • slow speech

  • slurred speech

  • sore throat

  • sores, ulcers, or white spots on lips or in mouth

  • stiffness of limbs

  • stupor

  • sudden loss of consciousness

  • sweating

  • swelling of face, ankles, legs, or hands

  • swollen glands

  • talking, feeling, and acting with excitement

  • trouble in holding or releasing urine

  • trouble sleeping

  • twisting movements of body

  • unable to sleep

  • uncontrolled movements, especially of face, neck, and back

  • unpleasant breath odor

  • unsteadiness, awkwardness, trembling, or other problems with muscle control or coordination

  • unusual behavior

  • unusual bleeding or bruising

  • unusual tiredness or weakness

  • vomiting of blood

  • weakness in arms, hands, legs, or feet

  • weight gain or loss

  • yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:


Symptoms of Overdose
  • Change in consciousness

  • clumsiness

  • decreased awareness or responsiveness

  • difficulty sleeping

  • disorientation

  • disturbed concentration

  • drowsiness to profound coma

  • enlarged pupils

  • extreme fatigue

  • hallucination

  • increased or excessive unconscious or jerking movements

  • loss of consciousness

  • low body temperature

  • muscle aches

  • muscle weakness

  • pale skin

  • severe sleepiness

  • shivering

  • weak or feeble pulse

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Incidence not known
  • Abdominal cramps

  • bigger, dilated, or enlarged pupils (black part of eye)

  • black tongue

  • bloating

  • decreased interest in sexual intercourse

  • diarrhea

  • difficulty having a bowel movement (stool)

  • disturbance of accommodation

  • enlargement of the breast

  • hair loss, thinning of hair

  • heartburn

  • hives or welts

  • inability to have or keep an erection

  • increased in sexual ability, desire, drive, or performance

  • increased interest in sexual intercourse

  • increased sensitivity of eyes to light

  • increased sensitivity of skin to sunlight

  • loss in sexual ability, desire, drive, or performance

  • pain or discomfort in chest, upper stomach, or throat

  • peculiar taste

  • redness or other discoloration of skin

  • severe sunburn

  • small red or purple spots on skin

  • swelling of the breasts or breast soreness in both females and males

  • swelling of the testicles

  • swelling or inflammation of the mouth

  • swollen, painful, or tender lymph glands on side of face or neck

  • unexpected or excess milk flow from breasts

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Surmontil side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Surmontil resources


  • Surmontil Side Effects (in more detail)
  • Surmontil Use in Pregnancy & Breastfeeding
  • Drug Images
  • Surmontil Drug Interactions
  • Surmontil Support Group
  • 1 Review for Surmontil - Add your own review/rating


  • Surmontil Prescribing Information (FDA)

  • Surmontil Concise Consumer Information (Cerner Multum)

  • Surmontil Monograph (AHFS DI)

  • Surmontil MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Surmontil with other medications


  • Depression


Thursday, September 13, 2012

Ketoconazole Shampoo



Pronunciation: kee-toe-KOE-na-zole
Generic Name: Ketoconazole
Brand Name: Nizoral A-D


Ketoconazole Shampoo is used for:

Treating scaling associated with dandruff. It may also be used for other conditions as determined by your doctor.


Ketoconazole Shampoo is an imidazole antifungal. It works by killing sensitive fungi by interfering with the formation of the fungal cell membrane and weakening it. The weakened cell membrane allows the cell contents to leak out and results in the death of the fungus.


Do NOT use Ketoconazole Shampoo if:


  • you are allergic to any ingredient in Ketoconazole Shampoo

Contact your doctor or health care provider right away if any of these apply to you.



Before using Ketoconazole Shampoo:


Some medical conditions may interact with Ketoconazole Shampoo. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have low blood sugar levels, liver disease, or porphyria (a blood disease), sulfite sensitivity, or you drink more than 3 alcohol-containing drinks a day

Some MEDICINES MAY INTERACT with Ketoconazole Shampoo. Because little, if any, of Ketoconazole Shampoo is absorbed into the blood, the risk of it interacting with another medicine is low.


Ask your health care provider if Ketoconazole Shampoo may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Ketoconazole Shampoo:


Use Ketoconazole Shampoo as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Moisten hair and scalp with water. Apply enough shampoo to wash your scalp and hair. Gently massage the entire scalp, leaving the shampoo on for about 5 minutes. Rinse thoroughly, then dry your hair as you normally do.

  • Keep Ketoconazole Shampoo out of your eyes, nose, and mouth. If this occurs, wash with water and contact your doctor, nurse, or pharmacist.

  • If you miss a dose of Ketoconazole Shampoo, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Ketoconazole Shampoo.



Important safety information:


  • Be sure to use Ketoconazole Shampoo for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

  • If you use topical products too often, your condition may become worse.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Some of these products contain sulfites. Sulfites may cause an allergic reaction in some patients (eg, asthma patients). If you have ever had an allergic reaction to sulfites, ask your pharmacist if your product has sulfites in it.

  • Talk to your doctor before you take Ketoconazole Shampoo if you drink more than 3 drinks with alcohol per day.

  • Using Ketoconazole Shampoo on hair that has been permanently waved may cause a loss of the curl.

  • Ketoconazole Shampoo should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ketoconazole Shampoo while you are pregnant. If you are or will be breast-feeding while you use Ketoconazole Shampoo, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Ketoconazole Shampoo:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Itching; mild irritation or stinging; oiliness and dryness of hair and scalp.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); increased or abnormal hair loss; reddening, blistering, peeling, itching, or burning of your skin.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Ketoconazole Shampoo:

Store Ketoconazole Shampoo between 59 and 77 degrees F (15 and 25 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ketoconazole Shampoo out of the reach of children and away from pets.


General information:


  • If you have any questions about Ketoconazole Shampoo, please talk with your doctor, pharmacist, or other health care provider.

  • Ketoconazole Shampoo is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Ketoconazole Shampoo. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Ketoconazole resources


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